Monitoring of pulmonary function in Pompe disease: a muscle disease with new therapeutic perspectives.

M onitoring of pulmonary function and timely initiation of noninvasive ventilation should be a focus in supportive care for patients with muscular disorders. In the current issue of the European Respiratory Journal, PELLEGRINI et al. [1] focus on this aspect in patients with lateonset Pompe disease (glycogenosis type II, acid maltase deficiency) [1]. In Pompe disease, correct monitoring of pulmonary function and initiation of supportive care is even more relevant since new therapeutic developments are underway. The first reports on the effects of enzyme therapy for this disease are promising [2–4].